Mazen Animal Health Receives Key Patent

Patent Covers PEDV Sequence Expression in Plants and Plant-Produced Vaccines

AMES, Iowa, Feb. 15, 2023 – Mazen Animal Health Inc., a pioneer animal health company developing novel maize-based vaccines announced today it has been issued a patent for its transformative technology to produce orally delivered animal vaccines. The United States Patent and Trademark Office (USPTO) has issued U.S. Patent US-11566255-B2, “Expression of PEDV Sequences in Plants and Plant Produced Vaccine for Same” on January 31, 2023. This patent covers foundational technology for the company’s first vaccine product, which is anticipated for launch in 2024.

Porcine Epidemic Diarrhea Virus (PEDV) is a virus of widespread concern, causing diarrhea, vomiting and severe dehydration. The disease has a death rate from 80%-100% in infected piglets. PEDV prevention in neonatal pigs is challenging as the virus is highly infectious and able to survive in the environment even with strict sanitation practices.

Mazen’s first product will provide effective, lactogenic immunity to piglets through orally delivered maize-produced PEDV antigens dosed to the sows during gestation. “This initial patent marks a major milestone for the company, allowing us to protect our products as we move forward with our game-changing, unique approach to animal vaccines,” said Jennifer Filbey, PhD, CEO of Mazen. “We anticipate this is the first in many patents to come.”

Mazen’s PEDV patent builds on an established portfolio covering the underlying platform technology developed by John Howard, PhD, one of the company’s founders. Mazen holds an exclusive license to the platform for use in the field of animal health.

About Mazen Animal Health, Inc.

Mazen is developing and commercializing orally delivered animal vaccines that revolutionize animal disease prevention. Mazen provides elegant solutions to the challenges associated with injectable vaccines and offers customers (1) increased production system ROI — improving the economic and labor thresholds that control the vaccination decision today; (2) a safer method of vaccine administration for both animals and workers; (3) optimized vaccine efficacy, allowing for reduced antibiotic use; and (4) vaccines with a global reach because of ambient temperature stability and ease of delivery.

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