The Oralogics™ Technology Platform
Our Oralogics™ Technology Platform uses molecular farming to develop our vaccines. This technology allows the vaccine to be dosed through the animal’s feed instead of injected. Our vaccination approach is not only capable of increasing animal welfare, worker safety and biosecurity; oral vaccination also allows us to leverage mucosal immunity, the first line of defense against pathogens and diseases.
Unlocking Mucosal Immunity
Animal vaccines bring many advantages to the farmer – they prevent disease, decrease losses, reduce antibiotic use in animals and protect the human food supply chain.
However, many diseases aren't effectively controlled by traditional injectable vaccination as the systemic immune response is not attenuated quickly enough to mount a defense.
Fortunately, the vaccine technology Mazen is developing will offer an alternative approach to this practice. The gut mucosa is the site of first exposure to pathogens in production animals and where secretory IgA is produced to robustly respond to these pathogens. This response provides a quicker immune response, resulting in protection against rapidly spreading diseases. Oral vaccination through feed unlocks this robust immune response, protecting animals immediately from the disease attack.
Protein Design
We start by selecting the subunit antigens necessary to best address the target disease. These proteins are designed to result in maximum expression in the plant and to stimulate the greatest immune response.
Testimonials
See what others are saying about our revolutionary technology platform!
"Mazen’s vaccine constructs appear to be the most promising in regard to improving piglet survivability and condition following a virulent PEDv challenge."
- Ryan Saltzman, DVM
"Mazen is at the forefront of molecular farming technologies that leverage plants as natural production factories for recombinant proteins and other high value molecules."
- Eric O’Brien
Co-Founder and Managing Director of Fall Line Capital
“When we saw this technology, we thought this is a tremendous fit because corn is such a constant fixture in about every diet across the species. We certainly want to see this succeed.”
- Kale Causemaker
Senior Director of Sales and Innovative Solutions at Kent Nutrition Group
"We are excited that Mazen Animal Health will be expanding its R&D operations in the state. Both crop science and animal health are strengths in the state’s ag tech ecosystem, and Mazen is in both."
- Paul Ulanch Ph.D
Senior Director of Focused Initiatives, NC Biotechnology Center